BIOSKINREPAIR

InjuryActinic Keratosis

Actinic keratosis is one of the most common sun-induced pre-cancerous skin lesions and precursor of squamous cell carcinoma as well as basal cell carcinoma cancer. If treated early, almost all actinic keratosis can be eliminated without becoming skin cancers.

An actinic keratosis is most likely to appear on the face, ears, scalp, neck, backs of the hands and forearms, shoulders, and lips - the parts of the body most often exposed to sunshine. The growths may be flat and pink or raised and rough.

Risks of Actinic Keratosis
The morphology of atypical cells in both actinic keratosis and squamous cell carcinoma is identical. The risk of progression to squamous cell carcinoma (the most common form of skin cancer) is minimal. But up to 60% of squamous cell carcinoma cases begin as actinic keratosis.

Preventing Actinic Keratosis
Apply a broad spectrum sunscreen
(protects against both UVA and UVB rays) that has a Sun Protection Factor (SPF) of 15 or more, every day.

Avoid deliberate tanning.
Even when wearing sunscreen, sunbathing is not safe. Tanning beds and sunlamps are not safe alternatives because they too emit UV rays.

Stay out of the sun between 10 a .m. and 4 p.m.
This is when the sun's rays are the strongest. Seek shade whenever possible. If you don't see your shadow or your shadow is shorter than you, it is important to seek cover.

Wear protecting clothing when you are on the sun.
A wide-brimmed hat is a must to protect your face and neck from the harmful rays. Wear sunglasses that provide 100% UV protection.

How is developed:

• Individuals with light skin are most likely to develop actinic keratosis. In fact, fair-skinned individuals living in sunny climates have over 50 percent chance of developing actinic keratosis. Individuals aged 40 and up are at high risk, with more men affected by this common, pre-cancerous condition than women. Furthermore, regardless of age, all individuals with blue eyes and or childhood freckling are at a higher risk for actinic keratosis. 

(1)During periods of depressed immunity, the visible and the subclinical lesions flare and become inflammatory red and scaly. This depression of the immune system can occur following intense ultraviolet light exposure or with systemic chemotherapy for other carcinomas.

(2)Over the years, the lesions gradually progress, and approximately 1 in 20 lesions eventually turn into invasive carcinomas. These lesions are typically redder and inflamed, elevated, and indurate lesions.



Actinic Keratosis Treatment Options

Regression of actinic keratosis occurs when sun exposure is decreased and mild lesions are healed. 

Treatment is often indicated to prevent the cells from invading the dermis and possibly metastasizing. If a lesion exhibits evidence of possible dermal invasion, such as marked erythema (redness of the skin caused by dilatation and congestion of the capillaries, often a sign of inflammation or infection) ulceration, tenderness, bleeding, and especially indurations (hardening of a normally soft tissue), a physician will consider performing a biopsy. 

Non Surgical Treatment

As lesions progress , they can be treated with topical 5-fluorouracil. This medication is applied twice daily for a period of 3-4 weeks for facial lesions. Other body sites require longer treatment, with the arms needing 6-8 weeks. Is better treating the entire area of involvement

.

During the treatment phase , the lesions become increasingly red, and small subclinical lesions become visible. This treatment can be temporarily disfiguring, with inflammatory and red ulcerations and crust formation. However, if the patient completes the treatment, the lesions usually heal within 2 weeks of stopping treatment, the complexion is smooth, and the actinic keratosis is improved.

Topical 5-fluorouracil treatment can be repeated on several occasions. The few residual lesions that are not completely cleared with 5-fluorouracil then can be treated surgically.

Photodynamic therapy (PDT) can also be used to treat multiple actinic keratoses. In this treatment, topical 5-aminolevulinic acid accumulates preferentially in the dysplastic cells. On exposure to irradiation with light of an appropriate wavelength, oxygen free radicals are generated and cell death results. Patients experience pain in the areas treated, which is similar in quantity to the pain resulting from topical 5-fluorouracil. One treatment with PDT appears to be as effective as 5-fluorouracil and may be considered in patients with contact sensitivity to 5-fluorouracil.



Surgical Treatment:
Early lesions of actinic keratoses can be treated with destruction. Cryotherapy with liquid nitrogen is the most effective and practical method for treating actinic keratoses when a limited number of lesions are present. Liquid nitrogen, applied by swab or spray, is used for several seconds. As the cryotherapy wound heals, the actinic keratosis is sloughed off. These patients may need periodic re-treatment for small recurrences or for new lesions. Often, semiannual or annual monitoring and treatment are warranted.

Physical destruction using electrodesiccation (destruction of lesions or sealing off of blood vessels by monopolar high-frequency electric current) and curettage (scrapping of tissues with an instrument shaped like a scoop or spoon) is particularly effective when a person has hyperkeratotic lesions (scaly or hardenned keratin proteins on the surface of the skin).

Chemical peels may be used in patients with a number of facial lesions

Dermabrasion may be used.

Adverse reactions such as scarring, textural changes, infection, and pigmentation alteration rarely occur.

Cryosurgery may result in wounds, require time for wound healing, and may yield hypopigmentation (white spots) or scarring and although those side effects were acceptable in the past, many people now developing actinic keratosis have little tolerance for any time for wound healing or any cosmetic changes.

The best therapy is thus one that addresses minor actinic keratosis scaly formations early, and here is where Bio Beauty Care plays a significant role.

Bio Beauty Care action:

  • Grinds down mild actinic keratosis and prevents the growth of new actinic keratosis scaly formations
  • Acts as an exfoliant eliminating dead cells and scaly lesions before they grow.
  • Also destroys pathogens, heals and regenerates damaged tissue.
  • It nourishes your skin and protects it from free radicals.
  • Improves the skin's elasticity, and leaves it silky soft and soothed.
  • Bio Beauty Care is a non prescription, natural skin care remedy, with absolutely no side effects.

    The active element in the cream is a natural biological ingredient, collected from live land snails, the same they use to quickly repair their own skin and shell when damaged. It is contained in the mucin secreted by the snails, (we gather it through a process that is safe for them). It is a viscose liquid that is made into an odorless white cream with no alien, synthetic chemicals.

    Analysis of the mucin has determined that it contains activators of skin growth factors and antimicrobial peptides. Also presents natural anti-inflammatory and immune modulating proteins, glycoproteins, glycosaminoglycans (a group of polysaccharides with high molecular weight that contain amino sugars and often form complexes with proteins. Also called mucopolysaccharide) and copper.

    The bioactive ingredients act as:

  • Regulators of enzyme activity;
  • Regulators of neurite outgrowth,
  • Anti-inflammatory agents that limits oxidative damage after tissue injury;
  • Stabilizers, cofactors, and/or co-receptors for (1) proteins produced by the human body that enable cells to communicate and effectively coordinate activities between one another (growth factors), (2) intracellular messenger molecules whose major function is to attract immune cells to sites of infection (chemokines), and (3) regulatory proteins released by cells of the immune system that act as intercellular mediators in the generation of an immune response (cytokines).

  • The results are:

  • a healthier appearance of the skin
  • a thicker skin
  • normal skin color,
  • normal skin texture and
  • a hydrated skin

  • Depending on the treatment method used, people may remain free of Actinic Keratosis for months and possibly years. However, individuals with significant photodamage and those who fail to minimize sun exposure are at increased risk for the development of additional Actinic Keratosis, as well as skin cancer.

    Bio Beauty Care will not heal severe keratosis that may have already a cancerous formation. Bio Beauty Care is a natural cosmetic product, not a drug or pharmaceutical product.



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